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KMID : 0882420150890040457
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Korean Journal of Medicine
2015 Volume.89 No. 4 p.457 ~ p.460
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A Case of Salicylate-Intoxication-Induced Pseudohyperchl
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Kim Hyo-Jong
Oh You-Jeong
Lee Jeong-Seok
Oh Sang-Yu
Lee Jong-Yoon
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Abstract
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Despite the increasing use of alternative analgesic agents, salicylate overdose remains a not-uncommon problem. Severe poisoning is life threatening, so prompt treatment and supportive measures are required to reduce mortality. Generally, salicylate intoxication results in the development of high-anion-gap metabolic acidosis. However, outside of Korea, normal-anion-gap or negative-anion-gap metabolic acidosis with hyperchloremia is rarely reported. We report herein the case of an 83-year-old female patient with chronic aspirin intake who presented with hyperchloremia and a negative anion gap. The patient’s symptoms improved with conservative treatment and hemodialysis; notably, her chloride levels decreased as her blood salicylate concentrations decreased. Salicylate may cause hyperchloremia, demonstrating the importance of careful documentation of patient medication histories.
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KEYWORD
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Salycylate intoxication, Pseudohyperchloremia, Hemodialysis
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